MK6-83 ( MK6 83; MK683 )

Catalog No. M27779 CAS No. 1062271-24-2

MK6-83 is the transient receptor potential channel ML3 agonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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2MG	37	Get Quote
5MG	59	Get Quote
10MG	87	Get Quote
25MG	177	Get Quote
50MG	311	Get Quote
100MG	530	Get Quote
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Biological Information

Product Name

MK6-83
Note

Research use only, not for human use.
Brief Description

MK6-83 is the transient receptor potential channel ML3 agonist.
Description

MK6-83 is the transient receptor potential channel ML3 agonist.(In Vitro):MK6-83(0.2-30 μM) shows no signs of cytotoxicity. Administration of 0-10 μM MK6-83 for 24 hours is efficacious on fibroblast lysosomes isolated from R403C or V446L expressing cells and has no significant effect on lysosomes isolated from TRPML1-/- fibroblasts.
Synonyms

MK6 83; MK683
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

Akt; mTOR; Microtubule/Tubulin; Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

1062271-24-2
Formula Weight

336.5
Molecular Formula

C16H20N2O2S2
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1ccc(s1)S(=O)(=O)Nc1ccccc1N1CCCCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jason E Faris,et al. A phase 2 study of oral MKC-1, an inhibitor of importin-β, tubulin, and the mTOR pathway in patients with unresectable or metastatic pancreatic cancer.Invest New Drugs. 2012 Aug;30(4):1614-20.

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