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n-Butylidenephthalide

CAS No. 551-08-6

n-Butylidenephthalide( Butylidenephthalide | BP | 3-Butylidene Phthalide )

Catalog No. M18790 CAS No. 551-08-6

(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.

Purity : >98% (HPLC)

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10MG	51	In Stock
25MG	85	In Stock
50MG	124	In Stock
100MG	178	In Stock
200MG	267	In Stock
500MG	461	In Stock
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Biological Information

Product Name

n-Butylidenephthalide
Note

Research use only, not for human use.
Brief Description

(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
Description

Butylidenephthalide is an inhibitor of platelet-derived growth factor (PDGF). Butylidenephthalide activity leads to the reduction of liver fibrosis, increased Nur77 (NR4A1) expression, and downregulation of EMT-related genes such as Snail (Snail/SNAI1) and Slug (Slug/SNAI2).
In Vitro

3-Butylidenephthalide (Butylidenephthalide) abrogates the myofibroblasts activation and mesenchymal transdifferentiation in oral submucous fibrosis.
In Vivo

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Synonyms

Butylidenephthalide | BP | 3-Butylidene Phthalide
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

α-glucosidase
Research Area

——
Indication

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Chemical Information

CAS Number

551-08-6
Formula Weight

188.22
Molecular Formula

C12H12O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (1328.23 mM)
SMILES

CCCC=C1C2=CC=CC=C2C(=O)O1
Chemical Name

3-Butylidene-2-benzofuran-1-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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