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n-Butylidenephthalide

CAS No. 551-08-6

n-Butylidenephthalide ( Butylidenephthalide; BP; 3-Butylidene Phthalide )

Catalog No. M18790 CAS No. 551-08-6

(Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.

Purity : 98%

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Biological Information

  • Product Name
    n-Butylidenephthalide
  • Note
    Research use only, not for human use.
  • Brief Description
    (Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
  • Description
    Butylidenephthalide is an inhibitor of platelet-derived growth factor (PDGF). Butylidenephthalide activity leads to the reduction of liver fibrosis, increased Nur77 (NR4A1) expression, and downregulation of EMT-related genes such as Snail (Snail/SNAI1) and Slug (Slug/SNAI2).
  • Synonyms
    Butylidenephthalide; BP; 3-Butylidene Phthalide
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    α-glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    551-08-6
  • Formula Weight
    188.22
  • Molecular Formula
    C12H12O2
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    CCCC=C1C2=CC=CC=C2C(=O)O1
  • Chemical Name
    3-Butylidene-2-benzofuran-1-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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