MAP4K4-IN-11e

CAS No. 1774346-60-9

MAP4K4-IN-11e( MAP4K4 inhibitor 11e )

Catalog No. M12671 CAS No. 1774346-60-9

A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MAP4K4-IN-11e
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM.
  • Description
    A potent, selective, ATP-competitive inhibitor of MAP4K4 with IC50 of 1.9 uM, without effect on other stress pathway related kinases; is active at much lower concentration in the cellular neurite outgrowth assay and may exhibit better pharmacokinetic properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MAP4K4 inhibitor 11e
  • Pathway
    MAPK/ERK Signaling
  • Target
    MAP4K
  • Recptor
    MAP4K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1774346-60-9
  • Formula Weight
    301.342
  • Molecular Formula
    C17H19NO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-hexanoyl-4-hydroxy-5-(4-hydroxyphenyl)pyridin-2(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schr?der P, et al. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403.
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