MAP4K4-IN-44

CAS No. 1623464-28-7

MAP4K4-IN-44( —— )

Catalog No. M12396 CAS No. 1623464-28-7

MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MAP4K4-IN-44
  • Note
    Research use only, not for human use.
  • Brief Description
    MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay.
  • Description
    MAP4K4-IN-44 is a potent, moderately selective small molecule MAP4K4 inhibitor with IC50 of 5 nM in LC3K assay, demonstrates favorable in vivo bioavailability in mouse.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    MAP4K
  • Recptor
    MAP4K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1623464-28-7
  • Formula Weight
    349.398
  • Molecular Formula
    C18H19N7O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-methyl-1-(4-(4-(pyridin-4-ylamino)pyrrolo[2,1-f][1,2,4]triazin-6-yl)-1H-pyrazol-1-yl)propan-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang L, et al. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4546-4552.
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