inS3-54-A26, a novel inhibitor of the DNA-binding domain (DBD) of STAT3, suppresses tumor growth, metastasis and STAT3 target gene expression in vivo.

β III probe

Soyasaponin Bb can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signaling pathways.