L-allo-Isoleucine

CAS No. 1509-34-8

L-allo-Isoleucine( (3R)-LS-Isoleucine | L(+)-Alloisoleucine )

Catalog No. M20000 CAS No. 1509-34-8

L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 35 In Stock
50MG 50 In Stock
100MG 72 In Stock
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Biological Information

  • Product Name
    L-allo-Isoleucine
  • Note
    Research use only, not for human use.
  • Brief Description
    L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder.
  • Description
    L-alloisoleucine is a branched chain amino acid and is a stereoisomer of L-isoleucine. It is a common constituent of human plasma (albeit at low levels). L-alloisoleucine is produced as a byproduct of isoleucine transamination. Plasma L-alloisoleucine which is derived from L-isoleucine in vivo can be used for the diagnosis of maple syrup urine disease (MSUD) a genetic disorder. Indeed plasma L-alloisoleucine levels above 5 μmol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    (3R)-LS-Isoleucine | L(+)-Alloisoleucine
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1509-34-8
  • Formula Weight
    131.17
  • Molecular Formula
    C6H13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC[C@@H](C)[C@H](N)C(O)=O
  • Chemical Name
    (2S3R)-2-Amino-3-methylpentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Schadewaldt P et al. Significance of L-alloisoleucine in plasma for diagnosis of maple syrup urine disease. Clin Chem. 1999 Oct;45(10):1734-40.
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