Cart
sales@molnova.com
Cav 2.2 blocker 1
CAS No. 1567335-29-8
Cav 2.2 blocker 1( —— )
Catalog No. M23678 CAS No. 1567335-29-8
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
|
| 5MG | 107 | In Stock |
|
| 10MG | 183 | In Stock |
|
| 25MG | 340 | In Stock |
|
| 50MG | 510 | In Stock |
|
| 100MG | 764 | In Stock |
|
| 200MG | 1004 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCav 2.2 blocker 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionCav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
-
DescriptionCav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorCav 2.2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1567335-29-8
-
Formula Weight424.96
-
Molecular FormulaC25H29ClN2O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:20 mg/mL (47.07 mM; Need ultrasonic)
-
SMILESCC1(C)CC(C2=NN(C3=CC=CC=C3OC)C(C4=CC=C(Cl)C=C4)=C2)CC(C)(C)O1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.
molnova catalog
related products
-
Ca2+ channel agonist...
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
-
Gallopamil hydrochlo...
Gallopamil hydrochloride is an antagonist of phenylalkylamine calcium. Gallopamil hydrochloride can be used in antiarrhythmic and vasodilator studies.
-
Sipatrigine
Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
