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Podocarpusflavone A

CAS No. 22136-74-9

Podocarpusflavone A( —— )

Catalog No. M37939 CAS No. 22136-74-9

Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Podocarpusflavone A
  • Note
    Research use only, not for human use.
  • Brief Description
    Podocarpusflavone A is a DNA topoisomerase I inhibitor with moderate anti-proliferative activity that induces cell apoptosis in MCF-7.
  • Description
    Podocarpusflavone A is a DNA topoisomerase I inhibitor. Podocarpusflavone A has moderated anti-proliferative activity andinduces cell apoptosis in MCF-7. Podocarpusflavone A is developing anti-tumor agents.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topoisomerase | STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22136-74-9
  • Formula Weight
    552.48
  • Molecular Formula
    C31H20O10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (90.50 mM; Ultrasonic )
  • SMILES
    COc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(=O)c4c(O)cc(O)cc4o3)c2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pen-Ho Yeh et al. Naturally Occurring Cytotoxic [3′→8″]-Biflavonoids from Podocarpus nakaii J Tradit Complement Med. 2012 Jul;2(3):220-6.?
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