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FLT3-IN-16

CAS No. 298207-49-5

FLT3-IN-16( —— )

Catalog No. M37680 CAS No. 298207-49-5

FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 113 Get Quote
25MG 251 Get Quote
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Biological Information

  • Product Name
    FLT3-IN-16
  • Note
    Research use only, not for human use.
  • Brief Description
    FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia .
  • Description
    FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia.
  • In Vitro
    FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    298207-49-5
  • Formula Weight
    301.36
  • Molecular Formula
    C15H15N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (82.96 mM; Ultrasonic (<80°C)
  • SMILES
    NC(=O)c1c(NC(=O)c2cccnc2)sc2CCCCc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6.?
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