Home - Products - Angiogenesis - Chk - 4-Demethyldeoxypodophyllotoxin

4-Demethyldeoxypodophyllotoxin

CAS No. 3590-93-0

4-Demethyldeoxypodophyllotoxin( —— )

Catalog No. M37321 CAS No. 3590-93-0

4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 282 In Stock
10MG 464 In Stock
25MG 744 In Stock
50MG 986 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    4-Demethyldeoxypodophyllotoxin
  • Note
    Research use only, not for human use.
  • Brief Description
    4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.
  • Description
    4-Demethyldeoxypodophyllotoxin is an aryltetralin lignan that can be found in Podophyllum peltatum.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Chk
  • Recptor
    Chk
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3590-93-0
  • Formula Weight
    384.38
  • Molecular Formula
    C21H20O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1[C@@]2([C@@H](C=3C(C[C@]2(CO1)[H])=CC4=C(C3)OCO4)C5=CC(OC)=C(O)C(OC)=C5)[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. David E.Jackson, et al. Aryltetralin lignans from Podophyllum hexandrum and Podophyllum peltatum. Phytochemistry. 1984, 23 (5): 1147-1152.
molnova catalog
related products
  • SB-218078

    A potent inhibitor of Chk1 that blocks phosphorylation of cdc25 with IC50 of 15 nM.

  • MARPIN

    MARPIN is a novel ATR-Chk1 pathway inhibitor that inhibits hydroxyurea (HU)-induced phosphorylation of Ser345 on Chk1 with IC50 of 7.7 uM.

  • PV-1115

    A potent and highly selective Chk2 inhibitor with IC50 of 0.14 nM; displays greater than 100 uM for Chk1 in vitro.