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TIE-2/VEGFR-2 kinase-IN-5
CAS No. 1014407-83-0
TIE-2/VEGFR-2 kinase-IN-5( —— )
Catalog No. M37252 CAS No. 1014407-83-0
TIE-2/VEGFR-2 kinase-IN-5 (TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor) is a potent agent with anti-angiogenic activity, commonly used in biomedical research focused on angiogenesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
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| 5MG | 459 | Get Quote |
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| 10MG | 657 | Get Quote |
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| 25MG | 994 | Get Quote |
|
| 50MG | 1371 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTIE-2/VEGFR-2 kinase-IN-5
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NoteResearch use only, not for human use.
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Brief DescriptionTIE-2/VEGFR-2 kinase-IN-5 (TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor) is a potent agent with anti-angiogenic activity, commonly used in biomedical research focused on angiogenesis.
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DescriptionTIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. TIE-2/VEGFR-2 kinase-IN-5 also is a potent TIE-2 and VEGFR-2 tyrosine kinase inhibitor with pIC50 values of 7.78 nM and 8.11 nM, respectively. TIE-2/VEGFR-2 kinase-IN-5 can be used for the research of angiogenesis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetVEGFR
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RecptorVEGFR | Tie-2
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Research Area——
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Indication——
Chemical Information
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CAS Number1014407-83-0
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Formula Weight481.35
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Molecular FormulaC21H13F6N5O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC=1C=CC(=CC1)C2=COC3=NC=NC(N)=C32)NC=4C=C(C=C(C4)C(F)(F)F)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Miyazaki Y, et al. Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1773-8. ?
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