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Topoisomerase II inhibitor 14
CAS No. 305343-00-4
Topoisomerase II inhibitor 14( —— )
Catalog No. M37019 CAS No. 305343-00-4
Topoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis and blocks the cell cycle in S phase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 141 | In Stock |
|
| 10MG | 205 | In Stock |
|
| 25MG | 326 | In Stock |
|
| 50MG | 421 | In Stock |
|
| 100MG | 581 | In Stock |
|
| 200MG | 768 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTopoisomerase II inhibitor 14
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NoteResearch use only, not for human use.
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Brief DescriptionTopoisomerase II inhibitor 14 is a potent topoisomerase II inhibitor with anticancer and antioxidant activities.Topoisomerase II inhibitor 14 induces apoptosis and blocks the cell cycle in S phase.
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DescriptionTopoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoisomerase | Apoptosis | Antioxidant | NO Synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number305343-00-4
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Formula Weight332.19
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Molecular FormulaC15H11Cl2N5
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Purity>98% (HPLC)
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Solubility——
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SMILESClC1=C(C2N3C=4C(NC3=NC(N)=N2)=CC=CC4)C=CC(Cl)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Al-Karmalawy AA, et al. Novel fused imidazotriazines acting as promising top. II inhibitors and apoptotic inducers with greater selectivity against head and neck tumors: Design, synthesis, and biological assessments. Eur J Med Chem. 2023 Nov 5;259:115661.?
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