Cart
sales@molnova.com
FC-116
CAS No. 2417298-29-2
FC-116( —— )
Catalog No. M36931 CAS No. 2417298-29-2
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 129 | In Stock |
|
| 5MG | 113 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 330 | In Stock |
|
| 50MG | 461 | In Stock |
|
| 100MG | 607 | In Stock |
|
| 200MG | 826 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFC-116
-
NoteResearch use only, not for human use.
-
Brief DescriptionFC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice.
-
DescriptionFC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis | Microtubule Associated
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2417298-29-2
-
Formula Weight369.39
-
Molecular FormulaC21H20FNO4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(=C(/C(=O)C1=CC(OC)=C(OC)C(OC)=C1)\C)\C=2C=3C(NC2)=CC(F)=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Liu X, et al. Fluoroindole chalcone analogues targeting the colchicine binding site of tubulin for colorectal oncotherapy. Eur J Med Chem. 2023 Sep 5;257:115540.?
molnova catalog
related products
-
BFC1108
BFC1108 targets Bcl-2 and converts it to a pro-apoptotic protein, inhibits the growth of triple-negative breast cancer xenografts with high Bcl-2 expression, inhibits breast cancer lung metastasis, and induces apoptosis of Bcl-2-expressing cancer cells.
-
Sulforaphene
Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
-
Talampanel
Talampanel is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity.
