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(E/Z)-GSK5182
CAS No. 2699724-40-6
(E/Z)-GSK5182( —— )
Catalog No. M36812 CAS No. 2699724-40-6
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 187 | In Stock |
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| 5MG | 170 | In Stock |
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| 10MG | 275 | In Stock |
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| 25MG | 503 | In Stock |
|
| 50MG | 731 | In Stock |
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| 100MG | 1097 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(E/Z)-GSK5182
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NoteResearch use only, not for human use.
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Brief Description(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers.
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Description(E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers. GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetROS
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RecptorROS | Estrogen/progestogen Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2699724-40-6
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Formula Weight417.54
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Molecular FormulaC27H31NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 75 mg/mL (179.62 mM; )
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SMILESCN(C)CCOC1=CC=C(C=C1)C(=C(CCCO)C1=CC=CC=C1)C1=CC=C(O)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kim JH, et al. Estrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses livercancer cell proliferation via induction of p21 and p27. Exp Mol Med. 2016 Mar 4;48:e213.?
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