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MJ33 lithium salt

CAS No. 1007476-63-2

MJ33 lithium salt( —— )

Catalog No. M35038 CAS No. 1007476-63-2

MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study of acute lung injury.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MJ33 lithium salt
  • Note
    Research use only, not for human use.
  • Brief Description
    MJ33 lithium salt is an inhibitor of NADPH oxidase type 2-mediated ROS generation, a fluorinated phospholipid analog that inhibits the phospholipase A2 (PLA2) activity of peroxiredoxin 6 (Prdx6), and is used in the study of acute lung injury.
  • Description
    MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    ROS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1007476-63-2
  • Formula Weight
    498.48
  • Molecular Formula
    C22H43F3LiO6P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=P(OC)(OC(COCC(F)(F)F)COCCCCCCCCCCCCCCCC)[O-].[Li+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fisher AB, Dodia C, Chander A, Jain M. A competitive inhibitor of phospholipase A2 decreases surfactant phosphatidylcholine degradation by the rat lung. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):407-11. ?
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