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Home - Products - Proteasome/Ubiquitin - Tyrosinase - Flanvotumab

Flanvotumab

CAS No. 1188277-05-5

Flanvotumab( —— )

Catalog No. M36794 CAS No. 1188277-05-5

Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Flanvotumab
  • Note
    Research use only, not for human use.
  • Brief Description
    Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody targeting tyrosinase-related protein (TYRP1), exhibiting potent antitumor activity through natural killer-mediated and antibody-dependent cell-mediated cytotoxicity (ADCC).
  • Description
    Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Tyrosinase
  • Recptor
    Tyrosinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1188277-05-5
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Khalil DN, et al. An Open-Label, Dose-Escalation Phase I Study of Anti-TYRP1 Monoclonal Antibody IMC-20D7S for Patients with Relapsed or Refractory Melanoma. Clin Cancer Res. 2016 Nov 1;22(21):5204-5210.?
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