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Monalizumab
CAS No. 1228763-95-8
Monalizumab( —— )
Catalog No. M36667 CAS No. 1228763-95-8
Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 938 | In Stock |
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| 10MG | 1311 | In Stock |
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| 25MG | 1881 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMonalizumab
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NoteResearch use only, not for human use.
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Brief DescriptionMonalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A).
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DescriptionMonalizumab (IPH2201) is an immune checkpoint inhibitor targeting Natural Killer Group 2A (NKG2A). Monalizumab, a humanized anti-NKG2A blocking mAb, increases IFN-γ production, thereby promoting NK cell effector functions. Monalizumab can be used for the research of head and neck squamous cell carcinoma (HNSCC).
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In Vitro——
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In VivoAnimal Model:immunodeficient mice xenografted with Cal-27 HLA-E high tumor cellDosage:50?μg, together with 8?millions of activated NK cells Administration:intratumoral injections Result:Shows a synergestic antitumor effect.Enhanced NK-cell killing, and induces lysis of tumor cells.
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Synonyms——
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PathwayAngiogenesis
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TargetChk
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RecptorChk | IFNAR
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Research Area——
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Indication——
Chemical Information
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CAS Number1228763-95-8
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Thorbald van Hall, et al. Monalizumab: inhibiting the novel immune checkpoint NKG2A. J Immunother Cancer. 2019 Oct 17;7(1):263.?
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