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PD-321852
CAS No. 622856-21-7
PD-321852( PD 321852 | PD321852 )
Catalog No. M15356 CAS No. 622856-21-7
A potent, reasonably selective Chk1 inhibitor with cell IC50 of 5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1233 | Get Quote |
|
| 50MG | 2502 | Get Quote |
|
| 100MG | 3330 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePD-321852
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, reasonably selective Chk1 inhibitor with cell IC50 of 5 nM.
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DescriptionA potent, reasonably selective Chk1 inhibitor with cell IC50 of 5 nM; potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines; inhibits gemcitabine-induced Rad51 focus formation, and depletes RAD51 proteins in pancreatic cancer cells.
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In Vitro——
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In Vivo——
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SynonymsPD 321852 | PD321852
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PathwayAngiogenesis
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TargetChk
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RecptorChk
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Research Area——
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Indication——
Chemical Information
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CAS Number622856-21-7
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Formula Weight468.33
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Molecular FormulaC24H19Cl2N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NC(C2=C1C3=C(C=C2C4=C(Cl)C=CC=C4Cl)N(CCCNC)C5=C3C=C(O)C=C5)=O
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Chemical Name4-(2,6-dichlorophenyl)-9-hydroxy-6-(3-(methylamino)propyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Parsels LA, et al. Mol Cancer Ther. 2009 Jan;8(1):45-54.
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