Cart
sales@molnova.com
SMN-C2
CAS No. 1446311-56-3
SMN-C2( —— )
Catalog No. M36532 CAS No. 1446311-56-3
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 242 | Get Quote |
|
| 5MG | 375 | Get Quote |
|
| 10MG | 610 | Get Quote |
|
| 25MG | 914 | Get Quote |
|
| 50MG | 1224 | Get Quote |
|
| 100MG | 1602 | Get Quote |
|
| 500MG | 3258 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSMN-C2
-
NoteResearch use only, not for human use.
-
Brief DescriptionSMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.
-
DescriptionSMN-C2, an analog of RG-7916, is a selective modulator of SMN2 gene splicing that acts by binding SMN2 pre-mRNA, thereby increasing far upstream element binding protein 1 (FUBP1) and KH-spliced RNA binding Protein affinity regulator protein (KHSRP) to the SMN2 pre-mRNA complex. SMN-C2 can be used in spinal muscular atrophy (SMA) research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA/RNA Synthesis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1446311-56-3
-
Formula Weight417.5
-
Molecular FormulaC24H27N5O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C1C(C=2N=C3N(C2)C=C(C)N=C3C)=CC=4C(O1)=CC(=CC4)N5C[C@H](C)N(CC)CC5
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jingxin Wang, et al. Mechanistic studies of a small-molecule modulator of SMN2 splicing. Proc Natl Acad Sci U S A. 2018 May 15;115(20):E4604-E4612.?
molnova catalog
related products
-
10-Formyl-5,8-dideaz...
10-Formyl-5,8-dideazafolic acid (CB3717) is a water-soluble analog of folic acid, also known as folate.
-
ART558
ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM). ART558 can be used for the research of cancer.
-
Tallimustine HCl
Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia.
