Cart
sales@molnova.com
5-Fluoroorotic acid
CAS No. 703-95-7
5-Fluoroorotic acid( —— )
Catalog No. M22866 CAS No. 703-95-7
5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 27 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name5-Fluoroorotic acid
-
NoteResearch use only, not for human use.
-
Brief Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
-
Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
Recptorthymidylate synthase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number703-95-7
-
Formula Weight174.09
-
Molecular FormulaC5H3FN2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (718.02 mM; Need ultrasonic)
-
SMILESO=C(C(NC1=O)=C(F)C(N1)=O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.P K Rathod , A Khatri, T Hubbert, W K Milhous,et al.Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro.Antimicrob Agents Chemother. 1989 Jul;33(7):1090-4.
molnova catalog
related products
-
Azoxymethane
Azoxymethane (AOM) is a DNA damaging agent that induces cancer and can be used in mouse models of colorectal cancer.
-
TH-588 hydrochloride
A potent and selective inhibitor of MTH1 protein with IC50 of 5 nM.
-
NSAH?
NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.A unique nonnucleoside small-molecule hRR inhibitor, naphthyl salicylic acyl hydrazone (NSAH), using virtual screening, binding affinity, inhibition, and cell toxicity assays.?NSAH binds to hRRM1 with an apparent dissociation constant of 37 μM, and steady-state kinetics reveal a competitive mode of inhibition.?
