Cart
sales@molnova.com
5-Fluoroorotic acid
CAS No. 703-95-7
5-Fluoroorotic acid( —— )
Catalog No. M22866 CAS No. 703-95-7
5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 27 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name5-Fluoroorotic acid
-
NoteResearch use only, not for human use.
-
Brief Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
-
Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
Recptorthymidylate synthase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number703-95-7
-
Formula Weight174.09
-
Molecular FormulaC5H3FN2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (718.02 mM; Need ultrasonic)
-
SMILESO=C(C(NC1=O)=C(F)C(N1)=O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.P K Rathod , A Khatri, T Hubbert, W K Milhous,et al.Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro.Antimicrob Agents Chemother. 1989 Jul;33(7):1090-4.
molnova catalog
related products
-
Homovanillic acid
Homovanillic acid is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.
-
Trifluridine
Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase.
-
JH-RE-06
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
