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5-Fluoroorotic acid
CAS No. 703-95-7
5-Fluoroorotic acid( —— )
Catalog No. M22866 CAS No. 703-95-7
5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 27 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name5-Fluoroorotic acid
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NoteResearch use only, not for human use.
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Brief Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
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Description5-Fluoroorotic acid is an inhibitor of thymidylate synthase. 5-Fluoroorotic is a selective agent in yeast molecular genetics.5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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Recptorthymidylate synthase
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Research Area——
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Indication——
Chemical Information
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CAS Number703-95-7
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Formula Weight174.09
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Molecular FormulaC5H3FN2O4
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (718.02 mM; Need ultrasonic)
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SMILESO=C(C(NC1=O)=C(F)C(N1)=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.P K Rathod , A Khatri, T Hubbert, W K Milhous,et al.Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro.Antimicrob Agents Chemother. 1989 Jul;33(7):1090-4.
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