UniPR505( —— )

Catalog No. M36518 CAS No. 2938227-14-4

UniPR505 is a potent EphA2 antagonist (IC50: 0.95 μM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

UniPR505
Note

Research use only, not for human use.
Brief Description

UniPR505 is a potent EphA2 antagonist (IC50: 0.95 μM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.
Description

UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 μM. UniPR505 displays anti-angiogenic properties.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Tyrosine Kinase
Target

Ephrin Receptor
Recptor

Ephrin Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2938227-14-4
Formula Weight

647.89
Molecular Formula

C39H57N3O5
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](OC(NCC)=O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(N[C@@H](CC=5C=6C(NC5)=CC=CC6)CC(O)=O)=O)C)[H])[H]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Incerti M, et al. Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties. Eur J Med Chem. 2020 Mar 1;189:112083. ?

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