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AWL-II-38.3
CAS No. 1135205-94-5
AWL-II-38.3( —— )
Catalog No. M28187 CAS No. 1135205-94-5
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 177 | In Stock |
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| 5MG | 169 | In Stock |
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| 10MG | 264 | In Stock |
|
| 25MG | 543 | In Stock |
|
| 50MG | 764 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2120 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAWL-II-38.3
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NoteResearch use only, not for human use.
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Brief DescriptionAWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.
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DescriptionAWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.(In Vitro):AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets .
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In VitroAWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets.
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetEphrin Receptor
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number1135205-94-5
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Formula Weight469.42
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Molecular FormulaC23H18F3N5O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 66.67 mg/mL (142.03 mM)
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SMILESCC1=CN(C=N1)C1=CC(=CC(=C1)C(F)(F)F)C(=O)NC1=CC=C(C)C(NC(=O)C2=CC=NO2)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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