AXC-715 trihydrochloride

CAS No. 2479276-17-8

AXC-715 trihydrochloride( —— )

Catalog No. M36450 CAS No. 2479276-17-8

AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 208 In Stock
10MG 341 In Stock
25MG 554 In Stock
50MG 749 In Stock
100MG 1004 In Stock
200MG 1358 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AXC-715 trihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings.
  • Description
    AXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    TLR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2479276-17-8
  • Formula Weight
    420.81
  • Molecular Formula
    C18H28Cl3N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (297.05 mM; Ultrasonic )
  • SMILES
    NC1=NC2=C(C=CC=C2)C3=C1N=C(CCCC)N3CCCCN.Cl.Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.
molnova catalog
related products
  • TLR7 agonist 3

    TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.

  • Semapimod hydrochlor...

    Semapimod (CNI 1493;AXD-455) is a tetravalent guanylhydrazone that acts as a selective inhibitor of cytokine-inducible arginine transport and NO production.

  • EPZ020411 2HCl

    EPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM).