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Glycerol phenylbutyrate
CAS No. 611168-24-2
Glycerol phenylbutyrate( HPN-100 )
Catalog No. M22928 CAS No. 611168-24-2
Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 10MG | 37 | In Stock |
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| 25MG | 56 | In Stock |
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| 50MG | 74 | In Stock |
|
| 100MG | 137 | In Stock |
|
| 200MG | 203 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGlycerol phenylbutyrate
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NoteResearch use only, not for human use.
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Brief DescriptionGlycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia.
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DescriptionGlycerol phenylbutyrate (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).Glycerol phenylbutyrate may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders. Glycerol phenylbutyrate also has the potential for the treatment of hyperammonemia. (In Vivo):Glycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders.
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In Vitro——
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In VivoGlycerol phenylbutyrate (GPB) has the potential for the treatment of hyperammonemia. Glycerol phenylbutyrate (GPB) may have therapeutic potential in additional conditions such as chronic hepatic encephalopathy or other inherited metabolic disorders.
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SynonymsHPN-100
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PathwayAutophagy
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TargetSigma receptor
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Recptorσ2
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Research AreaUrinary system
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IndicationUrea Cycle Disorders
Chemical Information
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CAS Number611168-24-2
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Formula Weight530.65
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Molecular FormulaC33H38O6
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (282.67 mM)
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SMILESO=C(CCCC1=CC=CC=C1)OC(COC(CCCC2=CC=CC=C2)=O)COC(CCCC3=CC=CC=C3)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rescifina A, et al. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis. Eur J Pharm Sci. 2017 Aug 30;106:94-101.
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