M3541

CAS No. 1360628-91-6

M3541( —— )

Catalog No. M36357 CAS No. 1360628-91-6

M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 236 In Stock
10MG 377 In Stock
25MG 635 In Stock
50MG 867 In Stock
100MG 1163 In Stock
200MG 1572 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    M3541
  • Note
    Research use only, not for human use.
  • Brief Description
    M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.
  • Description
    DNA-PK-IN-11 is a DNA-PK inhibitor with an IC50 of <0.1 μM (DE102010035744A1; compound 36).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | ATM/ATR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1360628-91-6
  • Formula Weight
    428.42
  • Molecular Formula
    C23H17FN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (11.67 mM; Ultrasonic (<60°C)
  • SMILES
    O=C1N(C=2C=3C(=CC(OC)=C(C3)C4=CN(C)N=C4)N=CC2N1C)C5=C(F)C=C(C#N)C=C5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dr. Fuchss Thomas, et al. Imidazolonylchinoline. DE102010035744A1.
molnova catalog
related products
  • HYPOCRELLIN B

    HYPOCRELLIN B are photosensitive pigments isolated from Hypocrella bambusae Sacc. Hypocrellin B causes DNA strand breakage induces apoptosis in ovarian cancer cells and inhibits proliferation of Staphylococcus by increasing ROS levels and damaging cell walls.

  • RA-9

    RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.

  • NBDHEX

    NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).