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M3541

CAS No. 1360628-91-6

M3541( —— )

Catalog No. M36357 CAS No. 1360628-91-6

M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    M3541
  • Note
    Research use only, not for human use.
  • Brief Description
    M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.
  • Description
    DNA-PK-IN-11 is a DNA-PK inhibitor with an IC50 of <0.1 μM (DE102010035744A1; compound 36).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis | ATM/ATR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1360628-91-6
  • Formula Weight
    428.42
  • Molecular Formula
    C23H17FN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (11.67 mM; Ultrasonic (<60°C)
  • SMILES
    O=C1N(C=2C=3C(=CC(OC)=C(C3)C4=CN(C)N=C4)N=CC2N1C)C5=C(F)C=C(C#N)C=C5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dr. Fuchss Thomas, et al. Imidazolonylchinoline. DE102010035744A1.
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