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TT-10

CAS No. 2230640-94-3

TT-10( —— )

Catalog No. M36310 CAS No. 2230640-94-3

TT-10 (TAZ-K), an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity, has potential application in heart disease research, specifically for conditions characterized by loss of cardiomyocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 75 In Stock
5MG 76 In Stock
10MG 122 In Stock
25MG 250 In Stock
50MG 392 In Stock
100MG 570 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    TT-10
  • Note
    Research use only, not for human use.
  • Brief Description
    TT-10 (TAZ-K), an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity, has potential application in heart disease research, specifically for conditions characterized by loss of cardiomyocytes.
  • Description
    TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss.
  • In Vitro
    TT-10 (48 h) markedly promotes cell cycle activation and increased cell division of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hiPSCMs).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    YAP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2230640-94-3
  • Formula Weight
    283.35
  • Molecular Formula
    C11H10FN3OS2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (176.46 mM; Ultrasonic )
  • SMILES
    Nc1nc(NCC=C)sc1C(=O)c1ccc(F)s1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Masamichi Ito, et al. Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2019 Mar;128:90-95.?
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