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HIV-1 inhibitor-54
CAS No. 2771211-71-1
HIV-1 inhibitor-54( —— )
Catalog No. M36014 CAS No. 2771211-71-1
HIV-1 inhibitor-54 is a potent inhibitor of WT HIV-1 (strain IIIB) in MT-4 cells, demonstrating anti-HIV activity with an EC50 of 32 nM. [HIV-1 inhibitor-54 can be used to study viral infections.]
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 409 | Get Quote |
|
| 10MG | 604 | Get Quote |
|
| 25MG | 908 | Get Quote |
|
| 50MG | 1251 | Get Quote |
|
| 100MG | 1647 | Get Quote |
|
| 500MG | 3312 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHIV-1 inhibitor-54
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NoteResearch use only, not for human use.
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Brief DescriptionHIV-1 inhibitor-54 is a potent inhibitor of WT HIV-1 (strain IIIB) in MT-4 cells, demonstrating anti-HIV activity with an EC50 of 32 nM. [HIV-1 inhibitor-54 can be used to study viral infections.]
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DescriptionHIV-1 inhibitor-54 is a potent HIV-1 inhibitor. HIV-1 inhibitor-54 has anti-HIV activity in MT-4 cells against WT HIV-1 (strain IIIB) with an EC50 value of 0.032 μM. HIV-1 inhibitor-54 can be used for the research of virus infection.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV Protease
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Research Area——
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Indication——
Chemical Information
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CAS Number2771211-71-1
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Formula Weight534.63
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Molecular FormulaC27H30N6O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=O)(C1=CC=2C(N1)=CC=C(NS(C)(=O)=O)C2)N3CCC(NC=4N=C(OC5=C(C)C=CC=C5C)C=CN4)CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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(S)-(+)-N-3-Benzylni...
(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19, which can be used to study HIV infection.
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Pitstop2
Pitstop2 is a selective inhibitor of amphiphysin association of clathrin terminal domain with an IC50 value of 12 μM. Pitstop2 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling.
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Apelin-36 (human)
Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
