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Cholesteryl Hemisuccinate
CAS No. 1510-21-0
Cholesteryl Hemisuccinate( —— )
Catalog No. M35918 CAS No. 1510-21-0
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 42 | In Stock |
|
| 1G | 58 | In Stock |
|
Biological Information
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Product NameCholesteryl Hemisuccinate
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NoteResearch use only, not for human use.
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Brief DescriptionCholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties.
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DescriptionCholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis | DNA/RNA Synthesis | Topoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number1510-21-0
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Formula Weight486.73
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Molecular FormulaC31H50O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 25 mg/mL (51.36 mM; Ultrasonic)DMSO : 10 mg/mL (20.55 mM; Ultrasonic )
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SMILES[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ray SD, et al. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J Pharmacol Exp Ther. 1996 Dec;279(3):1470-83.?
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