Cart
sales@molnova.com
Cholesteryl Hemisuccinate
CAS No. 1510-21-0
Cholesteryl Hemisuccinate( —— )
Catalog No. M35918 CAS No. 1510-21-0
Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 42 | In Stock |
|
| 1G | 58 | In Stock |
|
Biological Information
-
Product NameCholesteryl Hemisuccinate
-
NoteResearch use only, not for human use.
-
Brief DescriptionCholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties.
-
DescriptionCholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis | DNA/RNA Synthesis | Topoisomerase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1510-21-0
-
Formula Weight486.73
-
Molecular FormulaC31H50O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?Ethanol : 25 mg/mL (51.36 mM; Ultrasonic)DMSO : 10 mg/mL (20.55 mM; Ultrasonic )
-
SMILES[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCC(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ray SD, et al. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J Pharmacol Exp Ther. 1996 Dec;279(3):1470-83.?
molnova catalog
related products
-
NecroX-7
NecroX-7 is a small molecule necrosis modulator and potent antioxidant molecule.
-
β-Elemene
β-Elemene is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.β-Elemene significantly inhibited the metastatic capacity of MDR gastric cells in vivo and in vitro.?Mechanistically, β-Elemene regulated MMP-2/9 expression and reversed epithelial-mesenchymal transition.?
-
FMAU
FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.
