Cart
sales@molnova.com
BRD4-BD1-IN-2
CAS No. 2761321-26-8
BRD4-BD1-IN-2( —— )
Catalog No. M35765 CAS No. 2761321-26-8
BRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 μM, exhibiting 20-fold greater inhibitory activity against BRD4-BD1 compared to BRD4-BD2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 387 | In Stock |
|
| 10MG | 471 | In Stock |
|
| 25MG | 630 | In Stock |
|
| 50MG | 768 | In Stock |
|
| 100MG | 977 | In Stock |
|
| 200MG | 1283 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBRD4-BD1-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionBRD4-BD1-IN-2 is a selective and potent BRD4-BD1 inhibitor with an IC50 value of 2.51 μM, exhibiting 20-fold greater inhibitory activity against BRD4-BD1 compared to BRD4-BD2.
-
DescriptionBRD4-BD1-IN-2 is a selective BRD4-BD1 inhibitor, with an IC50 of 2.51 μM (20-times greater than that of BD2). BRD4-BD1-IN-2 can be used in studies of cancer and cardiovascular diseases.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetEpigenetic Reader Domain
-
RecptorEpigenetic Reader Domain
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2761321-26-8
-
Formula Weight583.07
-
Molecular FormulaC20H15Br3N4O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(N1C2=C(N=C1Br)N(C)C(=O)N(CC3=CC=C(Br)C=C3)C2=O)C4=CC=C(Br)C=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chang Y, et al. Design, synthesis, biological evaluation, and molecular docking of 1, 7-dibenzyl-substituted theophylline derivatives as novel BRD4-BD1-selective inhibitors. Medicinal Chemistry Research, 2021, 30(8): 1453-1468.
molnova catalog
related products
-
GSK046
GSK046 is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins(IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively).
-
BAZ1A-IN-1
BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity against cancer cells with low BAZ1A expression.
-
PNZ5
PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1.
