GLP-1R agonist 3
CAS No. 2428640-18-8
GLP-1R agonist 3( —— )
Catalog No. M35751 CAS No. 2428640-18-8
GLP-1R agonist 3 is a potent imidazole derivative and GLP-1R agonist with demonstrated research potential in diabetes. [Thickened]
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 195 | Get Quote |
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| 5MG | 297 | Get Quote |
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| 10MG | 487 | Get Quote |
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| 25MG | 908 | Get Quote |
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| 50MG | 1527 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameGLP-1R agonist 3
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NoteResearch use only, not for human use.
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Brief DescriptionGLP-1R agonist 3 is a potent imidazole derivative and GLP-1R agonist with demonstrated research potential in diabetes. [Thickened]
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DescriptionGLP-1R agonist 3 is a potent agonist of GLP-1R. GLP-1R agonist 3 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 3 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 1).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetGlucagon Receptor
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RecptorGlucagon Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2428640-18-8
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Formula Weight553.58
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Molecular FormulaC31H28FN5O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (225.80 mM; Ultrasonic )
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SMILESC(N1C=2C(N=C1CN3CCC(=CC3)C=4N=C(OCC5=C(F)C=C(C#N)C=C5)C=CC4)=CC=C(C(O)=O)C2)[C@@H]6CCO6
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Adomeglivant
A potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM.
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Bay 55-9837
Selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and >1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and >10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.
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Avexitide acetate
Avexitide acetate (exendin 9-39) is a potent glucagon-like peptide 1 receptor (GLP-1R) antagonist for the study of post-obesity hypoglycemia.
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