Aβ-IN-1( —— )

Catalog No. M35706 CAS No. 2766509-32-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Aβ-IN-1
Note

Research use only, not for human use.
Brief Description

Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
Description

Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM). Aβ-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ-IN-1 shows a sustained pharmacokinetic profile.
In Vitro

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In Vivo

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Synonyms

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Pathway

Neuroscience
Target

Gamma-secretase
Recptor

Gamma-secretase
Research Area

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Indication

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CAS Number

2766509-32-2
Formula Weight

483.77
Molecular Formula

C35H49N
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C=5C(CC2)=NC=6C(C5C)=CC=CC6)[H])[H]
Chemical Name

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