Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage it also has antifungal activity. Columbianetin has anti-inflammatory effects it promotes histamine release and inhibits the histamine release by substance P suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (2'S)-columbianetin can be effectively used to protect keratinocytes from UVB induced damage.

1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- can be used as a broad-spectrum antimicrobial agent with inhibitory activity against Aspergillus niger Bacillus subtilis, Pseudomonas albicans, Escherichia coli and Staphylococcus aureus.

Fluxapyroxad is a broad-spectrum fungicide that inhibits the succinate dehydrogenase (SQR) enzyme.