Trifloxystrobin

Research use only, not for human use.

Trifloxystrobin is a fungicide that inhibits the growth of R. solani isolates from sugar beet crops.EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos respectively.

Trifloxystrobin is a fungicide that inhibits the growth of R. solani isolates from sugar beet crops.EC50s of 23.0 μg/L and 1.7 μg/L for Daphnia magna neonate and embryos respectively.

ell Cytotoxicity Assay Cell Line:HaCaT cell Concentration:2 μM, 3.91 μM, 7.81 μM, 14.63 μM, 31.25 μM, 62.50 μM, 125 μM, 250 μM, 500 μM Incubation Time:24 h, 48 h Result:Decreased the cell viability in a concentration-dependent manner.Showed the IC50 value of cell viability at 24 h was calculated to be 22.9 μM, and that at 48 h was 5.14 μM.Apoptosis Analysis Cell Line:HaCaT cell Concentration:0.5 μM Incubation Time:24 h, 48 h Result:Induced the expression of pro-apoptotic proteins, apaf-1, procasp-9, procasp-8, and cyt c.Observed both only Annexin V-FITC (green)-positive cells and Annexin V-FITC (green)-/PI (red)-positive cells.

Animal Model:Zebrafish embryosDosage:30.0 μg/L, 37.5 μg/L, 47.0 μg/L, 58.6 μg/L Administration:Zebrafish embryos were exposed to trifloxystrobin Result:Caused severe developmental abnormalities of zebrafish embryos.Induced oxidative stress in embryos. Changed the transcription of immune related genes of embryos.

CGA 279202

Microbiology/Virology

Antifungal

Antifungal

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141517-21-7

408.37

C20H19F3N2O4

>98% (HPLC)

DMSO:125 mg/mL (306.09 mM)

CO/N=C(/C(=O)OC)c1ccccc1CO/N=C(\C)c1cccc(C(F)(F)F)c1

alphaE-(methoxyimino)-2-[[[(E)-[1-[3-(trifluoromethyl)phenyl]ethylidene]amino]oxy]methyl]-benzeneacetic acid methyl ester

(-20℃)

With Ice Pack

≥ 2 years