ML089

CAS No. 1306638-12-9

ML089( —— )

Catalog No. M35404 CAS No. 1306638-12-9

ML089 (CID-22416235) is an orally available and potent, selective inhibitor of phosphomannose isomerase (PMI), with potential inhibition of other PMI immediate homologs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML089
  • Note
    Research use only, not for human use.
  • Brief Description
    ML089 (CID-22416235) is an orally available and potent, selective inhibitor of phosphomannose isomerase (PMI), with potential inhibition of other PMI immediate homologs.
  • Description
    ML089 is a potent, selective, and orally available phosphomannose isomerase (PMI) inhibitor with an IC50 of 1.3 μM. ML089 can be used for the research of congenital disorder of glycosylation Ia.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1306638-12-9
  • Formula Weight
    245.27
  • Molecular Formula
    C13H8FNOS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (101.93 mM; Ultrasonic )
  • SMILES
    O=C1C2=CC(F)=CC=C2SN1C=3C=CC=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Russell Dahl,?et al. Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem.?2011 May 26;54(10):3661-8.?
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