Wistin

Research use only, not for human use.

Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist.

Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist.

Wistin, is a PPARγ agonist that can induce the mRNA expression of the PPARγ target gene adiponectin in mouse 3T3-L1 cells.Wistin inhibits cellular triglyceride accumulation in hepatocytes (P<0.05 at 10 μg/mL) in a dose-dependent manner.Wistin (10 μg/mL) results in a 2.5-, 7.2-, and 14.8-fold increase in the expression levels of CPT1a, ACO, and ACS, respectively.Treatment with Wistin for 48 h significantly decreases the amount of cellular TG in mouse primary hepatocytes in a dose-dependent manner.Treatment with wistin enhanced the marker of adipocyte differentiation, such as triglyceride accumulation in 3T3-L1 cells. RT-PCR Cell Line:Mouse hepatocytes.Concentration:1 or 10 μg/mL.Incubation Time:48 h.Result:Significantly increased PPARα mRNA levels in a dose-dependent manner.

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Others

Other Targets

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19046-26-5

460.4

C23H24O10

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years