Lurtotecan( —— )

Catalog No. M35356 CAS No. 149882-10-0

Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.

Purity : >98% (HPLC)

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Biological Information

Product Name

Lurtotecan
Note

Research use only, not for human use.
Brief Description

Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
Description

Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

Topoisomerase
Recptor

Topoisomerase
Research Area

——
Indication

——

Chemical Information

CAS Number

149882-10-0
Formula Weight

518.56
Molecular Formula

C28H30N4O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 4.33 mg/mL (8.35 mM; Ultrasonic )
SMILES

CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4c(CN4CCN(C)CC4)c3Cn1c2=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9.?

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