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FINO2

CAS No. 869298-31-7

FINO2( —— )

Catalog No. M35322 CAS No. 869298-31-7

FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FINO2
Note

Research use only, not for human use.
Brief Description

FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels.
Description

FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.
In Vitro

FINO2 (10 μM; 24 h) induce ferroptosis and shows iron dependence of lipid peroxidation in HT-1080 cells.
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Ferroptosis
Recptor

Ferroptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

869298-31-7
Formula Weight

256.38
Molecular Formula

C15H28O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (195.02 mM; Ultrasonic )
SMILES

CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gaschler MM, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515. ?

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