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FINO2
CAS No. 869298-31-7
FINO2( —— )
Catalog No. M35322 CAS No. 869298-31-7
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | Get Quote |
|
| 5MG | 123 | Get Quote |
|
| 10MG | 202 | Get Quote |
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| 25MG | 330 | Get Quote |
|
| 50MG | 490 | Get Quote |
|
| 100MG | 683 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFINO2
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NoteResearch use only, not for human use.
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Brief DescriptionFINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels.
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DescriptionFINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.
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In VitroFINO2 (10 μM; 24 h) induce ferroptosis and shows iron dependence of lipid peroxidation in HT-1080 cells.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetFerroptosis
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RecptorFerroptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number869298-31-7
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Formula Weight256.38
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Molecular FormulaC15H28O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (195.02 mM; Ultrasonic )
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SMILESCC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gaschler MM, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515. ?
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