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IMP-1710
CAS No. 2383117-96-0
IMP-1710( —— )
Catalog No. M34965 CAS No. 2383117-96-0
IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.IMP-1710 has antifibrotic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 453 | In Stock |
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| 5MG | 693 | In Stock |
|
| 10MG | 938 | In Stock |
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| 25MG | 1408 | In Stock |
|
| 50MG | 1822 | In Stock |
|
| 100MG | 2502 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIMP-1710
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NoteResearch use only, not for human use.
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Brief DescriptionIMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.IMP-1710 has antifibrotic activity.
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DescriptionIMP-1710 is a potent and selective deubiquitylating enzyme UCHL1 inhibitor with an IC50 value of 38 nM. IMP-1710 has antifibrotic activity. IMP-1710 is a UCHL1 probe to identify and quantify target proteins in intact human cells. IMP-1710 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number2383117-96-0
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Formula Weight381.43
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Molecular FormulaC23H19N5O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=O)(N1C=2C(=C(C=CC2)C=3C=4C(NC3)=NC=C(C#C)C4)CC1)[C@H]5N(C#N)CCC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Panyain N, et, al. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity. J Am Chem Soc. 2020 Jul 15;142(28):12020-12026.?
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