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IKK2-IN-4
CAS No. 354811-10-2
IKK2-IN-4( —— )
Catalog No. M34854 CAS No. 354811-10-2
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 276 | In Stock |
|
| 10MG | 424 | In Stock |
|
| 25MG | 656 | In Stock |
|
| 50MG | 866 | In Stock |
|
| 100MG | 1163 | In Stock |
|
| 200MG | 1553 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIKK2-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionIKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
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DescriptionIKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetIκB kinase (IKK)
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RecptorIκB/IKK | TNF
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Research Area——
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Indication——
Chemical Information
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CAS Number354811-10-2
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Formula Weight261.3
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Molecular FormulaC12H11N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C(N)=O)C=1SC(=CC1C(N)=O)C2=CC=CC=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Baxter A, et, al. Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2817-22.?
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