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Neticonazole
CAS No. 130726-68-0
Neticonazole( —— )
Catalog No. M34750 CAS No. 130726-68-0
Neticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 69 | In Stock |
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| 5MG | 31 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNeticonazole
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NoteResearch use only, not for human use.
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Brief DescriptionNeticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion.
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DescriptionNeticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects.
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In VitroWestern Blot Analysis Cell Line:C4-2B cells Concentration:10 μM Incubation Time:48 hours Result:Decreased the levels of both Alix and Rab27a, and significantly decreased nSMase2 levels.
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In VivoAnimal Model:Male C57BL/6 mice (8 weeks old) given ampicillin, neomycin, metronidazole and vancomycin, and injected with SW480 cells Dosage:1 ng/kg, 10 ng/kg and 100 ng/kg Administration:Oral gavage; daily; for 15 days Result:Significantly improved the survival of IDB mice with CRC xenograft tumors.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntifungal
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RecptorAntifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number130726-68-0
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Formula Weight302.43
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Molecular FormulaC17H22N2OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (826.64 mM; Ultrasonic )1M HCl : 100 mg/mL (330.66 mM; Ultrasonic; (HCL，pH≈1))
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SMILESC(=C\SC)(\C1=C(OCCCCC)C=CC=C1)/N2C=CN=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tsuboi R, et al. Hyperkeratotic chronic tinea pedis treated with neticonazole cream. Neticonazole Study Group. Int J Dermatol. 1996 May;35(5):371-3.?
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