SDH-IN-2

CAS No. 1823354-06-8

SDH-IN-2( —— )

Catalog No. M36610 CAS No. 1823354-06-8

SDH-IN-2, a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL, demonstrates antifungal activity against plant pathogenic fungi, with EC50 values ranging from 3.82 to 9.81 μg/mL.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 102 In Stock
10MG 159 In Stock
25MG 283 In Stock
50MG 417 In Stock
100MG 551 In Stock
200MG 728 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SDH-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    SDH-IN-2, a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL, demonstrates antifungal activity against plant pathogenic fungi, with EC50 values ranging from 3.82 to 9.81 μg/mL.
  • Description
    SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC50 values of 3.82-9.81 μg/mL for all the fungi. SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1823354-06-8
  • Formula Weight
    213.16
  • Molecular Formula
    C10H6F3NO
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1172.83 mM; Ultrasonic )
  • SMILES
    C(F)(F)(F)C1=CC=C(NC(C#C)=O)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang YH, et al. Discovery of N-Phenylpropiolamide as a Novel Succinate Dehydrogenase Inhibitor Scaffold with Broad-Spectrum Antifungal Activity on Phytopathogenic Fungi. J Agric Food Chem. 2023 Mar 1;71(8):3681-3693. ?
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