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L-Leucine-1-13C

CAS No. 74292-94-7

L-Leucine-1-13C( —— )

Catalog No. M34642 CAS No. 74292-94-7

L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

L-Leucine-1-13C
Note

Research use only, not for human use.
Brief Description

L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.
Description

L-Leucine-13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite | mTOR
Research Area

——
Indication

——

Chemical Information

CAS Number

74292-94-7
Formula Weight

132.17
Molecular Formula

C6CH13NO2
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 5 mg/mL (37.83 mM; Ultrasonic (<60°C)
SMILES

CC(C)C[C@H](N)[13C](O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. ?

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