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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - L-Leucine-1-13C

L-Leucine-1-13C

CAS No. 74292-94-7

L-Leucine-1-13C( —— )

Catalog No. M34642 CAS No. 74292-94-7

L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-Leucine-1-13C
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.
  • Description
    L-Leucine-13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
  • In Vitro
    Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite | mTOR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    74292-94-7
  • Formula Weight
    132.17
  • Molecular Formula
    C6CH13NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 5 mg/mL (37.83 mM; Ultrasonic (<60°C)
  • SMILES
    CC(C)C[C@H](N)[13C](O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. ?
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