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FPI-1523 sodium
CAS No. 1452459-52-7
FPI-1523 sodium( —— )
Catalog No. M35078 CAS No. 1452459-52-7
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 102 | Get Quote |
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| 5MG | 155 | Get Quote |
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| 10MG | 250 | Get Quote |
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| 25MG | 495 | Get Quote |
|
| 50MG | 707 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFPI-1523 sodium
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NoteResearch use only, not for human use.
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Brief DescriptionFPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively.
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DescriptionFPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity.
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In VitroFPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively.FPI-1523 sodium inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM).
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1452459-52-7
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Formula Weight344.27
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Molecular FormulaC9H13N4NaO7S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 125 mg/mL (363.08 mM; Ultrasonic)
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SMILESCC(NNC([C@H]1[N@@]2C(N([C@@](CC1)([H])C2)OS(=O)([O-])=O)=O)=O)=O.[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PE(18:1(9Z)/0:0)
PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner.
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2-Deoxyguanosine 5-m...
2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a GTP derivative that serves as an oxidizable target and is used in forming polycomplexes with other compounds.
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Campesterol
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions.
