Cart
sales@molnova.com
Gossypolone
CAS No. 4547-72-2
Gossypolone( —— )
Catalog No. M34612 CAS No. 4547-72-2
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 535 | In Stock |
|
| 5MG | 427 | In Stock |
|
| 10MG | 626 | In Stock |
|
| 25MG | 938 | In Stock |
|
| 50MG | 1293 | In Stock |
|
| 100MG | 1748 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 3515 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameGossypolone
-
NoteResearch use only, not for human use.
-
Brief DescriptionGossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
-
DescriptionGossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNeuroscience
-
TargetGamma-secretase
-
RecptorGamma-secretase | Wnt/beta-catenin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number4547-72-2
-
Formula Weight546.52
-
Molecular FormulaC30H26O10
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(=O)C1=C2C(=C(C(C)C)C(O)=C1O)C(=O)C(C)=C(C2=O)C=3C(=O)C=4C(C(=O)C3C)=C(C(C)C)C(O)=C(O)C4C=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lan L, et al. Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins. BMC Cancer. 2018 Aug 10;18(1):809.?
molnova catalog
related products
-
NVP-TNKS656
NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor.
-
YO-01027
YO-01027 (Dibenzazepine) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM for APPL and Notch cleavage, respectively.
-
PEAQX
PEAQX(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).
