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Gossypolone
CAS No. 4547-72-2
Gossypolone( —— )
Catalog No. M34612 CAS No. 4547-72-2
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 535 | In Stock |
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| 5MG | 427 | In Stock |
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| 10MG | 626 | In Stock |
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| 25MG | 938 | In Stock |
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| 50MG | 1293 | In Stock |
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| 100MG | 1748 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 3515 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGossypolone
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NoteResearch use only, not for human use.
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Brief DescriptionGossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
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DescriptionGossypolone is an RNA-binding protein Musashi-1 inhibitor with a Ki of 12 nM. Gossypolone disrupts the Musashi-numb RNA interaction and directly binds to the RBD1 of MSI1 protein. Gossypolone can be used for the research of cancer.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGamma-secretase
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RecptorGamma-secretase | Wnt/beta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number4547-72-2
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Formula Weight546.52
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Molecular FormulaC30H26O10
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Purity>98% (HPLC)
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Solubility——
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SMILESC(=O)C1=C2C(=C(C(C)C)C(O)=C1O)C(=O)C(C)=C(C2=O)C=3C(=O)C=4C(C(=O)C3C)=C(C(C)C)C(O)=C(O)C4C=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lan L, et al. Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins. BMC Cancer. 2018 Aug 10;18(1):809.?
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