Cart
sales@molnova.com
Ecopipam
CAS No. 112108-01-7
Ecopipam( —— )
Catalog No. M34581 CAS No. 112108-01-7
Ecopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | In Stock |
|
| 10MG | 176 | In Stock |
|
| 25MG | 353 | In Stock |
|
| 50MG | 554 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEcopipam
-
NoteResearch use only, not for human use.
-
Brief DescriptionEcopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively.
-
DescriptionEcopipam (SCH 39166) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam can be used for the research of schizophrenia and obesity.
-
In Vitro——
-
In VivoAnimal Model:Male young adult Long-Evans rats injected with Nicotine Dosage:0.003, 0.01, 0.03, 0.1, 0.3 mg/kg Administration:A single s.c. 20 min before Nicotine (0.1 mg/kg)Result:Dose-dependently reduced pressing on both active and inactive levers.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorDopamine Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number112108-01-7
-
Formula Weight313.82
-
Molecular FormulaC19H20ClNO
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN1[C@@]2([C@@](C=3C(=CC(Cl)=C(O)C3)CC1)(C=4C(CC2)=CC=CC4)[H])[H]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wu WL, et, al. Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists. J Med Chem. 2005 Feb 10;48(3):680-93. ?
molnova catalog
related products
-
Chlorpromazine
Chlorpromazine (CPZ) is a phenothiazine acting as dopamine antagonist.Chlorpromazine is a low-potency typical antipsychotic agent for the treatment of psychotic disorders such as schizophrenia.Chlorpromazine (CPZ) is a phenothiazine acting as dopamine antagonist.?
-
GBR-12935
GBR 12935 induced increase in the extracellular levels of dopamine to basal levels.
-
N-0500 HCl
N-0500 HCl is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the specific [3H]DP_x005f5,6-ADTN binding with IC50 of 3nM.
