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Home - Products - Metabolic Enzyme/Protease - MMP - PG-116800

PG-116800

CAS No. 291533-11-4

PG-116800( —— )

Catalog No. M34377 CAS No. 291533-11-4

PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 290 Get Quote
5MG 456 Get Quote
10MG 653 Get Quote
25MG 994 Get Quote
50MG 1362 Get Quote
100MG 1791 Get Quote
500MG 3528 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    PG-116800
  • Note
    Research use only, not for human use.
  • Brief Description
    PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
  • Description
    PG 116800 (PG 530742) is an orally avtive MMP inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    291533-11-4
  • Formula Weight
    501.55
  • Molecular Formula
    C24H27N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S(NC(CC#CCN1CCOCC1)C(O)=O)(=O)(=O)C2=CC=C(NC(=O)C3=CC=C(OC)C=C3)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Piotr Krzeski, et al. Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. Arthritis Res Ther. 2007;9(5):R109. ?
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