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Home - Products - Metabolic Enzyme/Protease - MMP - PG-116800

PG-116800

CAS No. 291533-11-4

PG-116800( —— )

Catalog No. M34377 CAS No. 291533-11-4

PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 456 In Stock
10MG 653 In Stock
25MG 1026 In Stock
50MG 1376 In Stock
100MG 1851 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    PG-116800
  • Note
    Research use only, not for human use.
  • Brief Description
    PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.
  • Description
    PG 116800 (PG 530742) is an orally avtive MMP inhibitor. PG 116800 has high affinity for MMP-2, -3, -8, -9, -13, and -14, while having substantially lower affinity for MMP-1 and -7. PG 116800 can be used for knee osteoarthritis research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    291533-11-4
  • Formula Weight
    501.55
  • Molecular Formula
    C24H27N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S(NC(CC#CCN1CCOCC1)C(O)=O)(=O)(=O)C2=CC=C(NC(=O)C3=CC=C(OC)C=C3)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Piotr Krzeski, et al. Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. Arthritis Res Ther. 2007;9(5):R109. ?
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