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CTS-1027
CAS No. 193022-04-7
CTS-1027( RS-130830 | Ro-1130830 | CTS1027 | CTS-1027 | RS130830 | Ro1130830 )
Catalog No. M13024 CAS No. 193022-04-7
A potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 869 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCTS-1027
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14.
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DescriptionA potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14, but not MMP1 and 7; displays little or no activity for other proteinases including caspases, the initiator and effector proteinases of apoptosis; attenuates hepatocyte apoptosis, liver injury and hepatic fibrosis, and is an attractive agent as a potential hepato-protective agent in HCV patients.HCV Infection Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsRS-130830 | Ro-1130830 | CTS1027 | CTS-1027 | RS130830 | Ro1130830
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PathwayMetabolic Enzyme/Protease
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TargetMMP
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RecptorMMP
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Research AreaInfection
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IndicationHCV Infection
Chemical Information
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CAS Number193022-04-7
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Formula Weight425.8832
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Molecular FormulaC19H20ClNO6S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESc1cc(ccc1Oc2ccc(cc2)Cl)S(=O)(=O)CC3(CCOCC3)C(=O)NO
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Chemical Name2H-Pyran-4-carboxamide, 4-[[[4-(4-chlorophenoxy)phenyl]sulfonyl]methyl]tetrahydro-N-hydroxy-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kahraman A, et al. Hepatol Res. 2009 Aug;39(8):805-13.
2. Liechti FD, et al. J Neuroinflammation. 2015 Mar 4;12:43.
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