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Gue1654

CAS No. 397290-30-1

Gue1654( —— )

Catalog No. M34274 CAS No. 397290-30-1

Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	112	Get Quote
5MG	167	Get Quote
10MG	245	Get Quote
25MG	549	Get Quote
50MG	975	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Gue1654
Note

Research use only, not for human use.
Brief Description

Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.
Description

Gue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

NF-κB
Recptor

NF-κB | PKC
Research Area

——
Indication

——

Chemical Information

CAS Number

397290-30-1
Formula Weight

447.6
Molecular Formula

C23H17N3OS3
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Bl?ttermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.?

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