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Gue1654
CAS No. 397290-30-1
Gue1654( —— )
Catalog No. M34274 CAS No. 397290-30-1
Gue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 112 | Get Quote |
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| 5MG | 167 | Get Quote |
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| 10MG | 245 | Get Quote |
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| 25MG | 549 | Get Quote |
|
| 50MG | 975 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameGue1654
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NoteResearch use only, not for human use.
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Brief DescriptionGue1654 is a selective OXE-R inhibitor that attenuates coronary artery ligation-induced ischemic myocardial injury and cardiomyocyte oxygen/glucose deprivation-induced injury in mice through activation of BCAT1.
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DescriptionGue1654 is a modulator of OXE-R. Gue1654 inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R. Gue1654 does not interfere nonspecifically with signaling directly at or downstream of Gβγ.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB | PKC
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Research Area——
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Indication——
Chemical Information
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CAS Number397290-30-1
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Formula Weight447.6
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Molecular FormulaC23H17N3OS3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=NC=2C=CC=3N=C(SC3C2S1)SC)C(C=4C=CC=CC4)C=5C=CC=CC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bl?ttermann S, et al. A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.?
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