Atractylodin( Atractydin )

Catalog No. M18797 CAS No. 55290-63-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Atractylodin
Note

Research use only, not for human use.
Brief Description

Atractylodin has high lipase inhibitory activity (IC5:39.12 μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83 μg/cm).
Description

Atractylodin has high lipase inhibitory activity (IC5:39.12 μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83 μg/cm). The repellency of Atractylodin (0.63 μg/cm) can achieve >90%.
In Vitro

Cell Viability Assay Cell Line:NCM460, SW480, HCT116 Concentration:1, 10, 25, 50, 100 μM Incubation Time:24 h Result:Decreased viability at a concentration of 100 μM in HCT116 cells.Western Blot Analysis Cell Line:HCT116 Concentration:50 μM Incubation Time:1 h Result:Inhibited TNF-α-induced phosphorylation of NF-κB p65.
In Vivo

Animal Model:DSS-Induced Colitis Mouse Model Dosage:40 mg/kg Administration:i.p.Result:Reduced colitis symptoms and increased survival rate.Animal Model:NAFLD mice model Dosage:20, 40, 80 mg/kg Administration:i.g.Result:Reduced the release of ALT, AST, ROS and MDA.
Synonyms

Atractydin
Pathway

Apoptosis
Target

NF-κB
Recptor

lipase
Research Area

Others-Field
Indication

——

1. Tao J, et al. Zhongguo Zhong Yao Za Zhi. 2011 Jan;36(1):27-31.

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