Cart
sales@molnova.com
Abt-288
CAS No. 948845-91-8
Abt-288( —— )
Catalog No. M34151 CAS No. 948845-91-8
ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 459 | Get Quote |
|
| 10MG | 657 | Get Quote |
|
| 25MG | 994 | Get Quote |
|
| 50MG | 1371 | Get Quote |
|
| 100MG | 1773 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAbt-288
-
NoteResearch use only, not for human use.
-
Brief DescriptionABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.
-
DescriptionABT-288 is a competitive, potent and selective histamine H3 receptor (H3R) antagonist. ABT-288 has Ki values of 1.9 and 8.2 nM for human and rat H3Rs, respectively. ABT-288 can be used in cognitive impairment research..
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetHistamine Receptor
-
RecptorHistamine Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number948845-91-8
-
Formula Weight372.46
-
Molecular FormulaC23H24N4O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN1C[C@@]2(N(CC[C@@]2(C1)[H])C3=CC=C(C=C3)C4=CC=C(C=C4)N5C(=O)C=CC=N5)[H]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Esbenshade TA, et al. Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist. J Pharmacol Exp Ther. 2012 Oct;343(1):233-45.?
molnova catalog
related products
-
Bavisant
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
-
Azelastine hydrochlo...
Azelastine HCl is a potent, second-generation, selective, histamine antagonist.
-
Noctone
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production.Ranitidine (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 uM.
